The crash occurred on Route 9 at Friendship Road in Howell Township at about 9:30 a.m. on Wednesday, May 18, Howell police said.
There were no children on the buses, police said on Facebook.
One motorist was trapped. Police confirmed two injuries.
A bus driver and one car driver were taken to Jersey Shore Medical Center with serious injuries, developing reports said.
Route 9 South at New Friendship Road was closed for the accident investigation.
Police asked motorists to avoid the area. Traffic was being detoured onto Friendship Road to Church Road.
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